WebHepatic 25 48 Fatty metamorphosis, focal necrosis, hemosiderin deposition, lymphocytic infiltration, bile duct proliferation, fibrosis, pseudo-lobule formation Renal 25 48 Nuclear hypertrophy of tubular epithelium . Prendergast et al. 1967 . 44 Rat (Sprague-Dawley) 8 M, 8 F 30 days 5 days/week . 6 hours/day WebJun 12, 2024 · The primary target is the cholangiocyte (CC), the cell type lining the bile duct that is responsible for bile modification and transport. ... this type of proliferation is observed after bile duct ligation or feeding of either α-naphthylisothiocyanate or lithocholic acid ... A cytokeratin-immunohistochemical study of focal nodular hyperplasia ...
Gallbladder, Epithelium - Hyperplasia - Nonneoplastic Lesion Atlas
WebAug 19, 2013 · Initial bile duct proliferation is not considered to represent pre-neoplasia and may be reversible after withdrawal of the agent (Schauer and Kunze 1976). Based on rodent carcinogenicity studies conducted by the NTP, chemically induced hepatocellular neoplasms are relatively common while neoplasms of the biliary tree are very uncommon … WebJul 3, 2024 · Nausea and vomiting. These are not common symptoms of bile duct cancer, but they may occur in people who develop an infection (cholangitis) as a result of bile … r c hobbies \\u0026 signs junction city ks
Focal Nodular Hyperplasia in Children : Journal of Pediatric ... - LWW
WebJun 23, 2014 · Nonneoplastic Lesion Atlas. A guide for standardizing terminology in toxicologic pathology for rodents WebFocal Nodular Hyperplasia in Children. Somech, Raz *; ... A percutaneous needle liver biopsy demonstrated nodular hyperplastic parenchyma surrounded by fibrous septa and bile duct proliferation accompanied by an inflammatory infiltrate with no evidence of malignancy . These findings confirmed the diagnosis of FNH. WebJun 2, 2016 · Rather, bile duct proliferation underpinned the increased fibrosis in ANIT-exposed Fib ... Asterisks indicate focal hepatocellular necrosis or bile infarcts. Images are ×200 except hematoxylin and eosin (H&E) stained sections in (C), which are ×100. (B,D) Area of necrosis was determined as described in “Methods.” (E) Representative ... sims 4 simlicy save file download