Phenotypic heterogeneity什么意思
WebMay 21, 2024 · Phenotypic heterogeneity—functional diversity among genetically identical cells—can permit division of labor and cooperative behaviors or serve as a bet-hedging … WebOct 1, 2016 · Phenotypic heterogeneity describes the variation that exists between individual cells, spores or other biological entities within genetically-uniform populations of fungi or other organisms. Studies over the last 10–15 years have successfully used laboratory- and modelling-based approaches to demonstrate the prevalence of …
Phenotypic heterogeneity什么意思
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WebMay 9, 2024 · In recognition of the continuum of phenotypic and genetic heterogeneity seen in T2D, we applied a data dimensionality reduction approach using reverse graph … WebAug 26, 2024 · The third level of phenotypic heterogeneity is related to cellular heterogeneity of the same strain in a specific microenvironment. Finally, we consider how …
WebWhile some forms of phenotypic noise may have little fitness impact, phenotypic heterogeneity involving binary phenotypes is argued in many cases to offer an evolutionary advantage, as a strategy to facilitate diversifying bet-hedging or division of labor [12,18]. In many cases, the genetic basis of phenotypic differentiation is known, and WebNational Center for Biotechnology Information
WebOct 29, 2024 · This phenotypic heterogeneity can significantly reduce the efficacy of monotherapies targeting a small number of lesions, but may confer synergy when combination therapies targeting different dimensions of tumor phenotypes are employed. Through integrative analysis, multiple ITH features, in particular phenotypic ITH, were … WebDec 18, 2013 · The selective value of phenotypic heterogeneity can be envisioned in certain cases (6, 20).Furthermore, theoretical analysis supports the view that randomly generated phenotypic diversity can increase the chances of survival when bacterial populations are subjected to rapid, severe, or complex environmental fluctuations (21, 22).Such bet …
WebMar 24, 2024 · First reported in 1999, germline runt-related transcription factor 1 (RUNX1) mutations are a well-established cause of familial platelet disorder with predisposition to …
teacher improvement plan paWebAug 6, 2024 · Heterogeneity may be present in any cell phenotype but, given the strong association between growth rate and persistence, phenotypic variation that influences … teacher improvement planWebOct 1, 2016 · In the context of microbiology, ‘phenotypic heterogeneity’ refers to the phenomenon whereby individual cells within clonally-derived populations, that have a … teacher improvement plan nycdoeWebFeb 12, 2024 · Cell heterogeneity, such as antibiotic heteroresistance and cancer cell heterogeneity, has been increasingly observed. To probe the underlying molecular mechanisms in the dynamically changing heterogeneous cells, a high throughput platform is urgently needed to establish single cell genotype-phenotype correlations. Herein, we … teacher improvement plan templateWebSpatial heterogeneity analysis shows that these changes are mainly affected by climate zone, water-related factors (precipitation, relative humidity, soil water), and their interactive effects. Characterizing of resilience changes as reference conditions for ecosystem management and restoration has significant implications in the context of ... teacher improvement program doeWebJun 5, 2024 · Phenotypic heterogeneity influencing dynamics and steady-state population level in chemostats under different energy availabilities. Chemostat cultivation of A. aurescens TC1 at all dilution rates (D) resulted in a steady-state residual substrate concentration in the range of 80–420 μg l −1 (Supporting Information Table S1). teacher in a university or faculty codycrossWebJan 26, 2024 · However, heterogeneity driven by contact-dependent or short-range cell–cell crosstalk cannot be evaluated with single cell transcriptomic approaches, as spatial and contextual information is lost. … teacher in 1800s