Sm-a-actin

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August undefined, 2024

WebbAlpha smooth muscle actin antibody (ab5694) stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary gland are also … WebbThe Actin Alpha 2 (ACTA2) gene encoding smooth muscle aortic actin, was isolated and characterized. It was found that the ACTA2 gene contains at least 9 exons (7). Alpha smooth muscle actin appears to play an important functional role in myofibroblast contraction and migration.

Elements of the smooth muscle alpha-actin promoter required in …

WebbActin (Smooth Muscle) (Concentrate) Clone 1A4. This antibody labels smooth muscle cells, myofibroblasts and myoepithelial cells. It is a useful aid for classification of leiomyomas, … Webb9 apr. 2024 · Frameshift mutation S368fs in the gene encoding cytoskeletal β-actin leads to ACTB-associated syndromic thrombocytopenia by impairing actin dynamics. Greve JN, et al. Eur J Cell Biol, 2024 Apr. PMID 35313204. A pan-cancer analysis of the prognostic and immunological role of β-actin (ACTB) in human cancers. inclusive healthy communities grant nj

Inhibition of eNOS by L-NAME resulting in rat hind limb ... - Nature

Webbα-Actinin 属于细胞骨架蛋白的血影蛋白家族。它最早被确认为肌动蛋白交联蛋白，在每个单体的氨基末端与肌动蛋白结合头形成反向平行同型二聚体。 α-actinin 可以与大量参与 … Webbalpha-Smooth muscle (alpha-sm) actin, an isoform typical of smooth muscle cells (SMC) and present in high amounts in vascular SMC, was demonstrated in the cytoplasm of … Webbwith the Rho kinase inhibitor Y-27632 (10 mM) or actin polymerization with latrunculin B (0.5 mM) significantly decreased the activity of SM22 and SM a-actin promot-ers. In contrast, increasing actin polymerization with jasplakinolide (0.5 mM) increased SM22 and SM a-actin promoter activity by 22-fold and 13-fold, respectively. incarnation\u0027s a9

Pathology Outlines - Actin, alpha smooth muscle type

Human Activin-A Is Expressed in the Atherosclerotic Lesion and Promotes …

WebbThe smooth muscle α-actin and γ-actin proteins are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. The α-smooth muscle actin (ACTA2) is … WebbTransforming growth factor (TGF)-b-induced expression of smooth muscle (SM)-a-actin is accompanied by expression and activation of serum response factor (SRF). (A) Human … incarnation\u0027s acWebbin Sm-a-actin content with increasing age were due, in part, to an increase in Sm-a-actin synthesis. However, in SMCs from 90- and 180-day-old rats, the fractional content of Sm-a-actin exceeded its fractional synthesis at a time when total Sm-a-actin content was increas- ing. This suggests that Sm-a-actin turns over more slowly in mature animals. inclusive healthcare

"WebbA smooth muscle antibody (SMA) is a type of antibody known as an autoantibody. Normally, your immune system makes antibodies to attack foreign substances like … " - Sm-a-actin

Sm-a-actin

Shear Stress Induces Phenotypic Modulation of Vascular

Webb5 juni 1999 · In this study, the presence of a contractile actin isoform, alpha-smooth muscle (alpha-SM) actin, was assessed by immunohistochemistry in normal calf meniscal tissue and in meniscal cells in 2- and 3-dimensional culture. Calf meniscus cells were seeded in type I and type II collagen-glycosaminoglycan (GAG) matrices. WebbSM a-actin promoter is regulated through combinatorial interactions between different factors. Transforming growth factor-b induced activity of the 125-bp rat SM a-actin promoter is dependent on both an intact transforming growth factor-bcontrol element and intact CArG boxes.18 Addition-ally, the homeodomain factor MHox activates SM a-actin

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WebbThermo Fisher nonmuscle beta actin emdb emd 27572 arora as huang hl heissler sm chinthalapudi k 2024 cryo em structure Nonmuscle Beta Actin Emdb Emd 27572 Arora As Huang Hl Heissler Sm Chinthalapudi K 2024 Cryo Em Structure, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. WebbSee all alpha smooth muscle Actin primary antibodies Description Mouse monoclonal [1A4] to alpha smooth muscle Actin Host species Mouse Tested applications Suitable …

WebbSmooth Muscle Actin ( Figures 25-3, A, and 25-4, A) The smooth muscle actin (SMA) marker has a relatively long track record of use as a myoepithelial marker in breast … Webbof SM a-actin expression involves a complex interaction of multiple positive and negative cis elements that act in a cell-type specific fashion.10–16 For example, a 547 bp SM a-actin promoter/CAT construct (p547CAT) had high activ-ity in cultured SMCs and in L6 skeletal myotubes, which are cell types that express SM a-actin in culture ...

Webb21 mars 2024 · GeneCards Summary for ACTA2 Gene. ACTA2 (Actin Alpha 2, Smooth Muscle) is a Protein Coding gene. Diseases associated with ACTA2 include Multisystemic Smooth Muscle Dysfunction Syndrome and Aortic Aneurysm, Familial Thoracic 6 . Among its related pathways are Actin Nucleation by ARP-WASP Complex and Integrin Pathway . Webb7 okt. 2024 · At E16.5, the expression of SM α-actin cannot detect in both control group and L-NAME treated group (Data not shown). At E17.5, SM α-actin expression observed in large vessels, as well as within ...

WebbSMC-specific marker genes including SM a-actin, SM myosin heavy chain, SM22, h-caldesmon, calponin, and telokin. The CArGs within any given SMC-specific promoter are …

Webbα-smooth muscle actin, a smooth muscle cell-specific protein, is also known as aortic smooth muscle or a smooth muscle actin (α-SMA, SMactin, α-SM-actin, ASMA). It belongs to the actin family.It is predominantly found in cells of the smooth muscle lineages. It has been reported that α-smooth muscle actin was also found in certain non-muscle ... inclusive healthy communities njWebbThe antibody (also known as anti-α-Sm-1) is specific for the single isoform of α-smooth muscle actin. It reacts specifically with α-smooth muscle actin in immunoblotting … incarnation\u0027s a2Webb5 feb. 2024 · Actins是球状多功能蛋白质的一个家族，形成微丝。 ACTA2是6种不同肌动蛋白亚型之一，参与平滑肌的收缩。 ACTA2（和所有actins一样）极其保守，几乎在所有哺乳动物中都有发现。在人类中，ACTA2由位于10q22-q24的ACTA2基因编码。该基因突变导致多种血管疾病，如胸主动脉疾病、冠状动脉疾病、中风、烟雾病和多系统平滑肌功能障 … inclusive healthcare centerWebb24 juni 2024 · Definition / general. Actin is a 43000 kDa ubiquitous protein found in all cells. Actins are involved in cell motility (alpha, smooth muscle) and the maintenance of the cytoskeleton (beta and gamma, all cells) … inclusive healthcare center myrtle beachWebb30 maj 2024 · Western blot results showed that the expression of SM-a-actin and SM-22a was increased, whereas the expression of MMP-2 and TNF-α was decreased in VSMCs treated with 3-MA, in relative to shear stress group (Fig. 4), suggesting that the induction of autophagy could partially block the phenotypic transition of VSMCs. incarnation\u0027s aaWebbOur Alpha-Smooth Muscle Actin monoclonal, polyclonal, recombinant monoclonal, cocktail and recombinant polyclonal antibodies are developed in Mouse, Rabbit and Goat. These antibodies have been verified by Relative expression and Cell treatment to confirm specificity to Alpha-Smooth Muscle Actin. inclusive hearts ability development centerWebba decrease in expression of SM-a-actin and increases in non-muscle b-actin expression (5). It is presumed that modulation of VSMC phenotype is me-diated through activation of specific signal transduction path-ways that act on transcription factors. In cultured VSMC, increases in SM-a-actin expression are observed in response to specific agonists. inclusive hearts madera